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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
22.12
Human Site:
S166
Identified Species:
37.44
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
S166
E
E
W
N
Q
M
Q
S
Q
E
D
E
V
A
I
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
S169
E
E
W
N
Q
M
Q
S
Q
E
D
E
V
A
I
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
S166
E
E
W
N
Q
M
Q
S
Q
E
D
E
V
A
I
Dog
Lupus familis
XP_535342
274
31382
S166
E
E
W
N
Q
M
Q
S
Q
E
D
E
V
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
S166
E
E
W
N
Q
M
Q
S
Q
E
E
E
A
A
I
Rat
Rattus norvegicus
O70257
261
29832
L167
I
T
E
D
D
L
R
L
I
H
E
R
E
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
K157
E
Q
D
L
E
L
I
K
E
R
E
T
A
I
K
Chicken
Gallus gallus
XP_001232002
272
30779
S164
E
D
W
S
Q
M
Q
S
Q
E
E
D
A
A
I
Frog
Xenopus laevis
NP_001079671
259
29246
I166
T
E
D
D
L
Y
L
I
E
E
R
E
T
A
I
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
V166
M
Q
T
E
E
E
P
V
T
E
E
D
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Q190
G
I
I
M
E
T
Q
Q
A
K
Q
T
L
A
D
Honey Bee
Apis mellifera
XP_396269
271
30684
Q166
R
T
Q
K
Q
I
Q
Q
Q
Q
L
Q
E
E
Q
Nematode Worm
Caenorhab. elegans
O16000
291
33234
G181
N
P
G
V
F
T
Q
G
I
I
T
D
T
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
R171
Q
A
L
L
L
Q
S
R
R
Q
E
V
V
F
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
6.6
66.6
33.3
6.6
N.A.
13.3
20
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
40
93.3
46.6
46.6
N.A.
33.3
40
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
8
0
0
0
22
58
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
15
8
0
0
0
0
0
29
22
0
0
8
% D
% Glu:
50
43
8
8
22
8
0
0
15
58
43
43
15
15
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
8
8
8
15
8
0
0
0
8
50
% I
% Lys:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
8
% K
% Leu:
0
0
8
15
15
15
8
8
0
0
8
0
15
0
15
% L
% Met:
8
0
0
8
0
43
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
36
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
15
8
0
50
8
65
15
50
15
8
8
0
8
15
% Q
% Arg:
8
0
0
0
0
0
8
8
8
8
8
8
0
0
0
% R
% Ser:
0
0
0
8
0
0
8
43
0
0
0
0
0
8
8
% S
% Thr:
8
15
8
0
0
15
0
0
8
0
8
15
15
0
0
% T
% Val:
0
0
0
8
0
0
0
8
0
0
0
8
36
0
0
% V
% Trp:
0
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _